目錄
Experiment 1 Preparation of Aspirin 1
Introduction 1
Experiment 2 Preparation of Paracetamo l8
Introduction8
Experiment 3 Preparation of Benorylate 13
Introduction13
Experiment 4 Preparation of Chlorobutanolum 18
Introduction18
Experiment 5 Preparation of Nikethamide 20
Introduction20
Experiment 6 Stability Study of Procaine Hydrochloride 24
Introduction24
Experiment 7 Preparation of Biphenyl Ketobutyric Acid 28
Introduction28
Experiment 8 Simple Distillation 33
Experiment 9 Melting Point Determination 35
Experiment 10 Recristallization 39
Experiment 11 Determination of Optical Rotation 42
the Laboratoty Report of Medicinal Chemistry 47
實(shí)驗(yàn)一 阿司匹林的制備 49
實(shí)驗(yàn)二 撲熱息痛的制備 52
實(shí)驗(yàn)三 苯樂來的制備 54
實(shí)驗(yàn)四 三氯叔丁醇的制備 57
實(shí)驗(yàn)五 尼克剎米的制備 59
實(shí)驗(yàn)六 鹽酸普魯卡因的穩(wěn)定性 61
實(shí)驗(yàn)七 聯(lián)苯丁酮酸的制備 63
實(shí)驗(yàn)八 簡單蒸餾 65
實(shí)驗(yàn)九 熔點(diǎn)測定 68
實(shí)驗(yàn)十 重結(jié)晶 70
實(shí)驗(yàn)十一 旋光度的測定 74
實(shí)驗(yàn)報(bào)告格式 78
Annex(附錄) 79